Where to buy saline for nebulizer

Two review authors independently performed study selection, data extraction, and assessment of risk of bias in included studies. We conducted random-effects model meta-analyses using Review Manager 5. We included a total of 28 trials involving infants with acute bronchiolitis, of whom infants received hypertonic saline.

Hospitalised infants treated with nebulised hypertonic saline had a statistically significant shorter mean length of hospital stay compared to those treated with nebulised 0. Infants who received hypertonic saline also had statistically significant lower post-inhalation clinical scores than infants who received 0. Twenty-four trials presented safety data: 13 trials infants, treated with hypertonic saline did not report any adverse events, and 11 trials infants, treated with hypertonic saline reported at least one adverse event, most of which were mild and resolved spontaneously.

Review question Is hypertonic saline solution via nebuliser effective and safe for the treatment of infants with acute bronchiolitis, compared to normal saline solution? Background Acute bronchiolitis is the most common lower respiratory tract infection in children aged up to two years. This is an update of a review previously published in , , and Key results Nebulised hypertonic saline may reduce hospital stay by 10 hours in comparison to normal saline for infants admitted with acute bronchiolitis.

The mean baseline CS scores and duration of illness were 5. Infants treated with bronchodilator therapy, oral steroids and antibiotics before admission was The maximum numbers of cases in each treatment group were reported in the age group 0—6 months and male preponderance in all the treatment groups was observed [ Table 2 ].

The CS scores before giving the specified therapy in the study population were 5. The results were compared with 0. The mean age of the patients in our study population was 5.

In our study, most of the children This is in accordance with the peak age of presentation of acute bronchiolitis. In our study, In our study, males were more affected than females from acute bronchiolitis.

This might be attributed to presence of two X chromosomes which produces greater genetic diversity to the female immunologic defense.

The mean duration of illness before study entry observed by Mandelberg et al. This was much less as compared to Kuzik et al. Kuzik et al. After treatment the 3 rd day CS scores dropped to 1. Hence, there was Thus, the effect of treatment was evident as a significant fall in CS scores in all the three groups. Sarrell et al. In a study conducted by Mandelberg et al. Also, the improvement in CS scores differed significantly on each of these days between the two groups.

Another study done by Kuzik et al. They only measured the length of hospital stay in response to therapy. It is possible that, in our study, an improvement in mucociliary transport and a better elimination of intracellular debris may have reduced viral load and decreased ongoing inflammation within the airways.

This might also have reduced an opportunity for secondary bacterial overgrowth and hereby may contribute to the favorable effect of decreasing post inhalation therapy clinical severity scores.

In our study, the mean duration of hospital stay was 3. In fact, the length of stay was reduced by as much as A similar reduction in the length of hospital stay has been observed by various other authors.

Mandelberg et al. In our study protocol, we did not encourage the use of bronchodilators along with the study solution. No side effects viz. It significantly reduces the CS scores and length of hospital stay as compared to 0. National Center for Biotechnology Information , U. Journal List Perspect Clin Res v. If you already have a nebulizer, call your healthcare provider for instructions.

Simply breathe in and out until the machine stops creating the vapor. This process can take 10 to 20 minutes at a time. For breathing issues, such as cough, you may need to use your nebulizer treatment multiple times per day for relief. Nebulizers can also be used for children, but only if they have a prescription from a pediatrician. Many pediatricians will administer a nebulizer on an outpatient basis for quick respiratory relief in children.

If your child has chronic breathing problems due to asthma, their healthcare provider may prescribe a device for use at home. Children may be able to breathe medications easier through a nebulizer, but some might find it difficult to sit still for the required time it takes to administer the entire liquid vial up to 20 minutes.

The exact treatment depends on whether the cough is acute or chronic, and whether your child has asthma or another underlying respiratory illness. As liquid is emitted through the machine, this type of device can be a breeding ground for mold. Follow the cleaning instructions that come with your nebulizer machine. You may be able to clean it with soap and sterile water, rubbing alcohol, or a dishwasher. Packaging: Sodium Chloride Inhalation Solution is available in 2. Interested in this product?

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